Pharmacology NCLEX-RN Practice Exam — Set 3
30 Pharmacology NCLEX-RN questions covering high-alert IV medications, antidotes, anticoagulants, antimicrobials, antipsychotics, anticonvulsants, and oncologic agents. Submit when finished for your score and full rationales.
Question 1
Endocrine SystemThe nurse is providing teaching to a client who has been prescribed sulfonylurea (glipizide) for type 2 diabetes mellitus. Which of the following instructions should the nurse include?
Question 2
Cardiovascular SystemThe nurse is assessing a client who is receiving a continuous infusion of heparin for treatment of a pulmonary embolism. The client's partial thromboplastin time (PTT) is 110 seconds (baseline 30 seconds). Which of the following actions should the nurse take?
Question 3
Immune SystemThe nurse is teaching a client who has been prescribed isoniazid (INH) for latent tuberculosis infection. Which of the following instructions should the nurse include?
Question 4
Psychiatric SystemThe nurse is caring for a client who has taken an overdose of a benzodiazepine medication. The client is somnolent but arousable, with a respiratory rate of 10 breaths per minute. Which of the following medications should the nurse anticipate administering?
Question 5
Neurologic SystemThe nurse is assessing a client who has been taking valproic acid for 8 months for generalized seizure disorder. The client's family reports increased confusion, lethargy, and nausea over the past 3 days. Which of the following laboratory values should the nurse obtain first?
Question 6
Cardiovascular SystemThe nurse is providing discharge teaching to a client who has been prescribed nitroglycerin sublingual tablets for angina pectoris. Which of the following instructions should the nurse include?
Question 7
Infectious Disease/Immune SystemThe nurse is caring for a client who is receiving intravenous acyclovir for herpes simplex encephalitis. The nurse notes that the client's urine output over the past 4 hours is 80 mL with a specific gravity of 1.035. Which of the following actions should the nurse take first?
Question 8
Neurologic SystemThe nurse is teaching a client who has been prescribed sumatriptan for acute migraine headaches. Which of the following statements by the client indicates a need for further teaching?
Question 9
Immune SystemThe nurse is preparing to administer an intravenous dose of amphotericin B to a client with disseminated fungal infection. Which of the following actions should the nurse take before starting the infusion?
Question 10
Endocrine SystemThe nurse is caring for a client who has been taking propylthiouracil (PTU) for 2 weeks for Graves' disease. The client reports a sore throat, fever, and mouth sores. Which of the following actions should the nurse take first?
Question 11
Respiratory SystemThe nurse is providing teaching to a client who has been prescribed tiotropium bromide via a dry powder inhaler for chronic obstructive pulmonary disease (COPD). Which of the following instructions should the nurse include?
Question 12
Psychiatric SystemThe nurse is assessing a client who has been taking duloxetine for 3 months for generalized anxiety disorder and diabetic peripheral neuropathy. The client reports new-onset yellowing of the skin and eyes. Which of the following actions should the nurse take?
Question 13
Cardiovascular SystemThe nurse is preparing to administer intravenous potassium chloride to a client with hypokalemia. The client's serum potassium level is 3.0 mEq/L (3.0 mmol/L). Which of the following actions is most important for the nurse to take before starting the infusion?
Question 14
Psychiatric SystemThe nurse is providing discharge teaching to a client who has been prescribed lurasidone for schizophrenia. Which of the following statements by the client indicates a need for further teaching?
Question 15
Cardiovascular SystemThe nurse is caring for a client who is receiving a continuous infusion of norepinephrine for septic shock. The nurse notes that the IV site is pale and cool with blanching extending 2 cm above the catheter insertion site. Which of the following actions should the nurse take first?
Question 16
Psychiatric SystemThe nurse is teaching a client who has been prescribed disulfiram for alcohol use disorder. Which of the following statements by the client indicates a correct understanding of the medication?
Question 17
Hematologic/Oncologic SystemThe nurse is assessing a client who is receiving intravenous mitoxantrone for metastatic breast cancer. The nurse notes that the client's urine has a blue-green discoloration. Which of the following actions should the nurse take?
Question 18
Endocrine SystemThe nurse is caring for a client who has been prescribed phentermine for weight loss. The client has a history of hypertension and coronary artery disease. Which of the following actions should the nurse take?
Question 19
Musculoskeletal SystemThe nurse is providing teaching to a client who has been prescribed risedronate for osteoporosis. The client has difficulty swallowing pills. Which of the following instructions should the nurse provide?
Question 20
Neurologic SystemThe nurse is assessing a client who is receiving a continuous infusion of propofol for sedation in the intensive care unit. Which of the following findings should prompt immediate intervention?
Question 21
Immune SystemThe nurse is preparing to administer intravenous immune globulin (IVIG) to a client with immune thrombocytopenia (ITP). The client's baseline immunoglobulin A (IgA) level is undetectable. Which of the following actions should the nurse take?
Question 22
Neurologic SystemThe nurse is providing discharge teaching to a client who has been prescribed memantine for moderate Alzheimer's disease. The client's caregiver asks how the medication works. Which of the following responses by the nurse is most accurate?
Question 23
Immune SystemThe nurse is caring for a client who has been prescribed linezolid for vancomycin-resistant Enterococcus (VRE) infection. The client also takes sertraline for depression. Which of the following adverse effects should the nurse monitor for?
Question 24
Endocrine SystemThe nurse is assessing a client who has been taking methimazole for 4 weeks for hyperthyroidism. The client reports joint pain and a rash on the arms. Which of the following actions should the nurse take?
Question 25
Neurologic SystemThe nurse is preparing to administer alteplase (tPA) to a client with acute ischemic stroke. The client's symptoms began 3 hours ago. Which of the following findings would be a contraindication to administering the medication?
Question 26
Integumentary SystemThe nurse is teaching a client who has been prescribed topical tacrolimus for atopic dermatitis (eczema). Which of the following instructions should the nurse include?
Question 27
Musculoskeletal SystemThe nurse is caring for a client who has been prescribed colchicine for acute gout flare. The client has a history of chronic kidney disease stage 4. Which of the following actions should the nurse take?
Question 28
Reproductive SystemThe nurse is assessing a client who has been taking oral contraceptives for 1 year. The client reports a new onset of severe headache, blurred vision, and shortness of breath. Which of the following conditions should the nurse suspect?
Question 29
Psychiatric SystemThe nurse is providing teaching to a client who has been prescribed varenicline for smoking cessation. Which of the following information should the nurse include?
Question 30
Hematologic/Oncologic SystemThe nurse is caring for a client who is receiving their first dose of rituximab intravenously for non-Hodgkin lymphoma. Fifteen minutes after starting the infusion, the client develops chills, fever, and difficulty breathing. Which of the following actions should the nurse take first?