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    Pharmacology NCLEX-RN Practice Exam — Set 2

    30 Pharmacology NCLEX-RN questions covering high-alert medications, antidotes, drug interactions, and nursing implications across body systems. Submit when finished for your score and full rationales.

    30 questions · Free · Rationales after submit

    Question 1

    Endocrine System

    The nurse is caring for a client who has been taking metformin for type 2 diabetes mellitus for 6 months. The client is scheduled for a computed tomography (CT) scan with intravenous contrast later today. Which of the following actions should the nurse take?

    Question 2

    Cardiovascular System

    The nurse is providing discharge teaching to a client who has been prescribed warfarin for atrial fibrillation. The client asks, "What should I do if I forget to take my morning dose?" Which of the following responses by the nurse is most appropriate?

    Question 3

    Cardiovascular System

    The nurse is assessing a client who was started on furosemide 40 mg orally twice daily three days ago for heart failure. The client reports feeling "weak and dizzy" when standing up. Which of the following actions should the nurse take first?

    Question 4

    Cardiovascular System

    The nurse is preparing to administer digoxin 0.25 mg orally to a client with heart failure. The client's apical pulse is 52 beats per minute and irregular. The client denies any chest pain or shortness of breath. Which of the following actions should the nurse take?

    Question 5

    Endocrine System

    The nurse is caring for a client who has been taking prednisone 40 mg daily for 2 weeks to treat an exacerbation of ulcerative colitis. The client asks the nurse, "Why is my face looking so round and puffy?" Which of the following responses by the nurse is most accurate?

    Question 6(Select all that apply)

    Respiratory System

    The nurse is teaching a client who has just been prescribed albuterol via metered-dose inhaler for exercise-induced bronchospasm. Which of the following instructions should the nurse include? Select all that apply.

    Question 7

    Reproductive System

    The nurse is assessing a client who is receiving a continuous intravenous infusion of magnesium sulfate for management of preeclampsia. The client's deep tendon reflexes are absent, and the respiratory rate is 10 breaths per minute. Which of the following actions should the nurse take first?

    Question 8

    Cardiovascular System

    The nurse is providing discharge teaching to a client who is being discharged with a prescription for amiodarone for the management of atrial fibrillation. Which of the following client statements indicates a need for further teaching?

    Question 9

    Gastrointestinal System

    The nurse is caring for a client who has taken an overdose of acetaminophen 2 hours ago in a suicide attempt. The client's serum acetaminophen level is 180 mcg/mL. Which of the following medications should the nurse anticipate administering?

    Question 10

    Endocrine System

    The nurse is assessing a client who has been taking levothyroxine for 3 months for hypothyroidism. The client reports feeling anxious, has a heart rate of 110 beats per minute, and has lost 8 pounds (3.6 kg) without trying. Which of the following actions should the nurse take?

    Question 11

    Cardiovascular System

    The nurse is caring for a client who has been prescribed spironolactone for heart failure. The client's laboratory results show a potassium level of 5.8 mEq/L (5.8 mmol/L). Which of the following actions should the nurse take first?

    Question 12

    Urinary and Renal System

    The nurse is providing teaching to a client who has been prescribed finasteride for benign prostatic hyperplasia. Which of the following statements by the client indicates correct understanding of the medication?

    Question 13

    Neurologic System

    The nurse is caring for a client who has been prescribed fentanyl transdermal patch for chronic cancer pain. The client's caregiver reports that the client is difficult to arouse and has a respiratory rate of 8 breaths per minute. Which of the following actions should the nurse take first?

    Question 14

    Neurologic System

    The nurse is assessing a client who has been taking phenytoin for 6 months for a seizure disorder. The nurse notes that the client has swollen, bleeding gums and difficulty chewing. Which of the following nursing actions is most appropriate?

    Question 15

    Psychiatric System

    The nurse is teaching a client who has been prescribed a nicotine transdermal patch for smoking cessation. The client asks, "Can I still smoke while wearing this patch?" Which of the following responses by the nurse is most appropriate?

    Question 16

    Endocrine System

    The nurse is caring for a client who received intravenous contrast 4 hours ago for a CT scan. The client received a dose of metformin this morning before the procedure. Which of the following laboratory values is most important for the nurse to monitor?

    Question 17

    Neurologic System

    The nurse is assessing a client who has been taking donepezil for 3 months for mild to moderate Alzheimer's disease. The client's spouse reports that the client has been having vivid nightmares and difficulty sleeping. Which of the following responses by the nurse is most appropriate?

    Question 18

    Immune System

    The nurse is preparing to administer intravenous vancomycin to a client with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. Which of the following actions should the nurse take during the infusion?

    Question 19

    Cardiovascular System

    The nurse is providing discharge teaching to a client who has been prescribed lisinopril for hypertension. Which of the following statements by the client indicates a need for further teaching?

    Question 20

    Reproductive System

    The nurse is caring for a client receiving an intravenous infusion of oxytocin for induction of labor at 40 weeks gestation. The client is now having contractions every 1.5 minutes lasting 90 seconds each. Which of the following actions should the nurse take?

    Question 21

    Cardiovascular System

    The nurse is assessing a client who has been taking clopidogrel for 2 weeks following a drug-eluting stent placement. The client reports black, tarry stools and generalized weakness. Which of the following laboratory values should the nurse anticipate checking first?

    Question 22

    Neurologic System

    The nurse is caring for a client who received a dose of intravenous morphine 30 minutes ago for postoperative pain. The client's respiratory rate is now 8 breaths per minute and the client is difficult to arouse. After administering naloxone, which of the following outcomes should the nurse expect?

    Question 23

    Psychiatric System

    The nurse is providing teaching to a client who has been prescribed a zolpidem for insomnia. The client asks, "Is this medication safe to take every night?" Which of the following responses by the nurse is most appropriate?

    Question 24

    Cardiovascular System

    The nurse is assessing a client who has been taking hydrochlorothiazide for 1 month for hypertension. The client reports muscle weakness and cramping. Which of the following electrolyte imbalances should the nurse suspect?

    Question 25

    Immune System

    The nurse is preparing to administer the first dose of ceftriaxone intravenously to a client with community-acquired pneumonia. The client reports a history of "an allergic reaction to penicillin" but cannot describe the reaction. Which of the following actions should the nurse take?

    Question 26

    Cardiovascular System

    The nurse is caring for a client who has been prescribed enoxaparin subcutaneously for deep vein thrombosis prophylaxis following hip replacement surgery. Which of the following actions should the nurse take when administering this medication?

    Question 27

    Musculoskeletal System

    The nurse is reviewing the laboratory results of a client who has been taking methotrexate for rheumatoid arthritis for 6 months. Which of the following findings is most concerning and requires immediate follow-up?

    Question 28

    Immune System

    The nurse is providing discharge teaching to a client who has been prescribed prednisone for a severe asthma exacerbation. The client is to take 60 mg daily for 5 days, then taper over 2 weeks. Which of the following statements by the client indicates a need for further teaching?

    Question 29

    Cardiovascular System

    The nurse is assessing a client who has been taking atorvastatin for 3 months for hyperlipidemia. The client reports new-onset muscle pain and weakness in both thighs. Which of the following actions should the nurse take first?

    Question 30

    Cardiovascular System

    The nurse is caring for a client who is receiving an intravenous infusion of dopamine for treatment of cardiogenic shock. The client's blood pressure is 80/50 mmHg, heart rate 110 beats per minute. Which of the following findings would indicate that the medication is having the desired therapeutic effect?